骨髓間充質(zhì)干細(xì)胞來(lái)源的miR-199a-5p通過(guò)抑制ZIK1/MAP3K11調(diào)節(jié)腎細(xì)胞癌細(xì)胞的增殖和侵襲
現(xiàn)代腫瘤醫(yī)學(xué)
頁(yè)數(shù): 6 2024-05-11
摘要: 目的:研究骨髓間充質(zhì)干細(xì)胞(bone marrow mesenchymal stem cells, BM-MSCs)來(lái)源的外泌體(exsome)中miR-199a-5p對(duì)腎細(xì)胞癌(renal cell carcinoma, RCC)細(xì)胞增殖和侵襲的影響。方法:分離骨髓間充質(zhì)干細(xì)胞來(lái)源的外泌體(BM-MSCs-Exo),電子顯微鏡觀察外泌體形態(tài),Western blot方法檢測(cè)外...